Foundations · Beginner
Start with the motor unit
Motor unit & electrophysiology
Identify whether you are recording a nerve response, a muscle response or one motor unit.
01Three different signals
- A SNAP sums synchronized sensory-fiber responses and is commonly measured in µV.
- A CMAP sums muscle-fiber responses after motor-nerve stimulation and is commonly measured in mV.
- A MUAP represents activity from one motor neuron and its muscle fibers within the needle's recording field.
02From signal to pathology
- Amplitude, latency, velocity and duration describe different features; none captures the whole pathology alone.
- NCS predominantly tests large myelinated fibers. Needle EMG assesses the motor system; routine testing does not directly measure small-fiber function.
03A useful sequence
- Ask about location first, then axonal or myelin features, timing and severity.
- Support each inference with the history, examination and multiple electrophysiological findings.
Pause and explain
Explain in your own words: “Identify the source of the signal before interpreting its numbers.” Then think of a situation in which it could be misinterpreted.
Show a review prompt
A low CMAP may reflect axonal loss, inadequate stimulation, NMJ dysfunction or muscle disease.
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References and further reading
- Basic Electrodiagnostics for the Referring Physician ↗AAPM&R KnowledgeNow · Society educational review · Link accessed 2026-09-08
- Neuroanatomy for Nerve Conduction Studies (2017) ↗AANEM · Anatomy course · Link accessed 2026-09-08
Educational synthesis; independent neuromuscular specialist review is pending. Publication dates and compilation dates are distinct. This is an original teaching synthesis; consult the source for complete methods and criteria.