Disease patterns · Advanced

Acquired demyelinating neuropathies

Acquired demyelinating neuropathies

Use formal criteria to avoid overcalling minor slowing.

3 learning sectionsCompiled 2026-09-08English edition · Traditional Chinese available

01A CIDP framework

  • Combine clinical time course, weakness/sensory distribution and multinerve evidence.
  • Apply the 2021 EAN/PNS motor and sensory requirements; phenotypes have different criteria.

02Common traps

  • Cold, compression sites, very low CMAPs and hereditary neuropathies can confound interpretation.
  • One prolonged distal latency or absent F wave does not turn every chronic weakness syndrome into CIDP.

03Consider MMN

  • Asymmetric motor-predominant deficits, preserved related sensory responses and non-entrapment block may suggest MMN.
  • Clinical integration remains necessary; failure to demonstrate block does not encompass every presentation.

Pause and explain

Explain in your own words: “Use criteria as a complete framework, not a selected numerical item.” Then think of a situation in which it could be misinterpreted.

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This is a learning framework. Use the original guideline and laboratory process for formal classification.

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References and further reading

Educational synthesis; independent neuromuscular specialist review is pending. Publication dates and compilation dates are distinct. This is an original teaching synthesis; consult the source for complete methods and criteria.